Biologist on a Bike: Coronavirus Insight from a Bike-Seat

J.C. on a bike:
J.C. is an academic [neuro]biologist turned bike-seat science journalist who moved to Pittsburgh in 2016. After nearly 20K miles on the streets of the City of Champions, J.C. calls Pittsburgh home. I hope you enjoy this very informative commentary and update from someone who is not only knowledgeable about the science background of this current pandemic, but also speaks a language we can all understand.  I hope readers here are ready to take ask a couple of research biologists a few questions which could be answered from a bike-seat in Pittsburgh.  I think it would be a mutually beneficial post to host and as long as J.C. is willing to answer questions during his ride, I will submit his commentary to Admin for posting to give this very innovative bike-seat journalist a chance to teach us all a thing or two about biology 101.
[J.C. discusses current issues framed by indepth background accomplished by  Harvard to the Bighouse, specifically “Logistical and Technical Exploration into the Origins of the Wuhan Strain of Coronavirus (COVID-19)”

 

From J.C. on a bike, summarized.
I am not a virologist, but I am a life-long biologist. And I can read about stuff. This is my 2nd attempt at a special episode about the current Coronavirus outbreak. (see below for the first video) Specifically, I am interested in cutting through the whirlwind of chatter on the internet speculating about the origin of this novel Coronavirus.
In this video, I tried to independently and objectively present real information which is out in the wild. First,  I give a quick and dirty introduction into the state of the field of Coronavirus, broadly speaking.
Next, I will address the literature sources I’ve cited regarding technologies which might be available, and I discuss whether folks in Wuhan likely were trained in these technologies. So far most of the circumstantial evidence is not helping to make  theories of highly nefarious activities fade away.
But is there a simpler explanation that doesn’t involve master plans of international bio-terrorism or crazy intergovernmental plots against whole cultures or races?
Long story short: It seems likely that the virus 2019-nCoV is a highly virulent virus that was accidentally released from a laboratory in Wuhan, China. It’s unfortunately hard to get reliable numbers simply because they seem to change all the time.
One this is certain: So far, it doesn’t seem to be going away like 2003 SARS-CoV did, so I believe it is warranted to stay aware and alert as the story evolves. The worst-case scenario is by all reasonable estimations still pretty serious, so let’s hope for better for China and the rest of the world than worst case
I will post any non-video updates in the description section below. Thanks for your time and attention.
Be well, and love your neighbors. J.C.

Below is the “first” video: J.C. on a bike, Coronavirus Part I.  https://www.youtube.com/watch?v=YL7c-vck4vk&t
J.C.  gave up lucrative careers as a Chicago Public School science teacher, pharmacy technician, and bartender before moving to the Netherlands to complete his PhD in Neurobiology in 2002.  He served as staff scientist at  both the Kavli Institute for Neuroscience at Norwegian Institute for Science and Technology (NTNU) in Trondheim Norway (2008-2012) and at Erasmus University Medical Center in Rotterdam, Netherlands (2012-2016).
Jay has been a Research Assistant Professor at the University of Pittsburgh School of Medicine since 2016.  As a science journalist, Jay is committed to hypothesis-driven science, deductive reasoning, and the free flow of Truth as the best means to achieve peace and well-being for all of humankind.

The primary initial impetus for this ride series were the following blogs, especially Harvard to the Big House.

(The author of the Harvard to the Big House, Dan, sent me the following bio to include. Seriously, Dan?  Please tell us more about how a NSA counterterrorism analyst ended up in prison.)

Dan is a NSA counterterrorism analyst who left that position to write an accessible, fast-paced distillation of everything you need to know about modern terrorism, which concludes that America’s gaps between her haves and have-nots will be the most likely source of violence. During his incarceration he spent 20 months as his prison’s special education tutor, and wrote extensively about the forces that draw humans together and push us apart, and reflecting upon how badly he’d screwed up. 

The scientist behind this article has dozens of peer-reviewed publications and 30 years of experience in genomic sequencing and analysis. He’s previously  worked at the Theoretical Biology Division of the Los Alamos National Laboratory, and later helped design several ubiquitous bioinformatic software tools while at another federal agency. If you’ve ever done any kind of scientific research, you’ve interacted with at least one of his projects.

Wow, Dan… that last line got my attention.  I look forward to finding out more about your background.

Legal Statement for both J.C. and Harvard to the Big House: Neither the scientist nor the blogger(s) are federally employed or connected to federal research.  This research and work has been accomplished and presented entirely using their own time and resources.

 

Twitter accounts for J.C. and Harvard, below.

https://mobile.twitter.com/jjcouey

https://mobile.twitter.com/harvard2h

1. Harvard to the Bighouse (@Harvard2H via twitter) https://harvardtothebighouse.com/2020…
2. James Lyons-Weiler Ph.D. (@lifebiomedguru via twitter) https://jameslyonsweiler.com/2020/01/…
3. Virology Blog (@profvrr via twitter) http://www.virology.ws/
Literature Review:
“Genomic characterization and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding” https://www.thelancet.com/journals/la… https://www.thelancet.com/action/show…
“Full-genome evolutionary analysis of the novel corona virus (2019-nCoV) rejects the hypothesis of emergence as a result of a recent recombination event” https://www.biorxiv.org/content/10.11… https://www.sciencedirect.com/science…
“SARS-like cluster of circulating bat coronavirus pose threat for human emergence” https://www.ncbi.nlm.nih.gov/pmc/arti…
“Human-animal interactions and bat coronavirus spillover potential among rural residents in Southern China” https://www.sciencedirect.com/science…
“Immunization with SARS coronavirus vaccines leads to pulmonary immunopathology on challenge with the SARS virus” https://www.ncbi.nlm.nih.gov/pubmed/2…
“Trypsin Treatment Unlocks Barrier for Zoonotic Bat Coronavirus Infection” https://jvi.asm.org/content/94/5/e017… https://jvi.asm.org/content/jvi/94/5/…
*Debunked article: “Uncanny similarity of unique inserts in the 2019-nCoV spike protein to HIV-1 gp120 and Gag” https://www.biorxiv.org/content/10.11…
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JC Onabike

Thanks for much for spreading the word. I am humbled.

This week’s update will add to the discussion of possible medical explanations for the many videos of collapsing victims in China and Iran. Dan and I have found some pretty strong evidence that Cononavirus has been known to have neurotrophic qualities, and there may even have been work to enrich these aspects of novel Coronaviruses to “understand these mechanisms better”. Viral infections which pass the blood-brain barrier would offer a quite plausible explanation for the rapid deterioration in some cases.

To reiterate, I am hoping to work with readers here to address questions that you might have (if I can) and to potentially find topics and directions that my reports can explore in the future.

Thanks again for welcoming me into your community.

jay (dude on bike)

Mygirl...maybe

Welcome JC Onabike: I’ve been castigated for stating that this virus is ‘not the flu’ and that it is far more serious than the flu. Many here refuse to believe that the virus is at all serious or that one should take it seriously.

So, what is your opinion? Serious? Not serious? What recommendations do you have regarding preparing for it and what suggestions might you give regarding amelioration of the situation?

mike
mike

Hi JC Onabike!
Please explain to us
why you accept by circumstantial evidence that the virus was produced and accidentally released in a Wuhan laboratory (this assumes an extraordinary high level of malevolence to create such, plus some incompetence)
but you refuse to consider that the same could have been produced by another actor, and deliberately set free near a Chinese virology lab just to make it look like an accident (only slightly higher level of malevolence, because if we produce it why don’t we use it? But we’re not gonna take the blame…)

Mista Shift
Mista Shift

JC and the Dan guy in the blog post JC refers to offer mountains of circumstantial evidence for an accidental release of a man made or man modified virus. They indicate that developing these bugs is a normal but dangerous practice for virology research and vaccine development. Develop a superbug to test your vaccines against. Polio was synthesized in 2000 and complete corona viruses within a few years. Mix and match Frankenstein research has been going on ever since. Several lab escapes have happened. This is all documented fact.

On the other hand, what evidence is there that it was an intentional release? There are many intriguing scenarios, but actual evidence? Zip.

mike
mike

You mean this one? https://harvardtothebighouse.com/2020/01/31/logistical-and-technical-analysis-of-the-origins-of-the-wuhan-coronavirus-2019-ncov/

Don’t you see how that article is pure propaganda: always assume the worst for your opponent, and always assume the best for your own side.
What is missing:
Any listing of the worst (known) handling cases in Western labs, for comparison.

And this
“the ACE2 receptor, which seems to be distributed in roughly equal proportions across global population”
is actually a clear lie, according to some documents I’ve seen.

Reading on, the linked website becomes a copy&paste dump, no ryhme or reason in the order the almost endless “facts” are presented.

“the accidental release of a bio-engineered virus meant for defensive immunotherapy research from Wuhan’s virology lab cannot be automatically discounted

So close proximity and cannot be discounted is their proof it was the Wuhan lab? Are you effing kidding me??

JC Onabike

To a certain extent, I get your point. But don’t let this discussion pivot on blame.

The key to Dan’s article is that it is likely:

1. Man made which could mean novel effects, etc.
2. It is more likely an accident than an attack.

You can agree or disagree with #2 and still appreciate the knowledge available in the article, and that’s what I try to do in the video.

I am not accusing China, but maybe more hoping that it was an accident.

If some other actor is attacking China with this bug and did it in such a way as to smear the Chinease while killing them…whoa. Then we are in big trouble.

There are those that say that’s indeed the case.

I am not one of them. I do get your argument. Leaking from a BSL4 laboratory is not the same as leaking from a BSL2/3 lab, and there is no previous history of BSL4 leaking anywhere on the planet. This was pointed out elsewhere.

mike
mike

Thanks.
I do believe we need to half-ways understand our psychopathic enemies, to be able to handle them. (Why only halfway? Because if you understand them fully, you are too close to becoming one yourself.)

Or as a wise man stated:
“Sometimes, if something particularly dreadful happened […], you might not be able to conjure up a philosophical or practical rationale for it. It might be too deep. If you are one unfortunate person, and someone truly malevolent got their mitts on you, that’s a Hell of a thing to try to make sense of. The only way you can make sense out of that is to come up with a comprehensive philosophy of evil […]”

Mista Shift
Mista Shift

Thanks for doing the research and the video J.C. On a Bike. So nice to see a report that is fact based instead of either spin or paranoia.

Mygirl...maybe

Well, I feel exonerated and terrified at the same time. I felt all along that this virus was engineered in the lab and released, hopefully by accident, on an unspecting populace. It remains doubtful that an immunity for the virus can be created in a person’s body, especially when the prospects of reinfection are present in the environment and when the inclusion of the HIV strand is taken into consideration.

This is a bio level 4 lab creation, the nastiest of the nasties and in those labs Racal suits are a must. If it is so contagious that it can enter via the eyes, well, that be bad. The masks and gloves and goggles are a start but, in reality, indadequate.
It will be interesting to see how those people who are infected and manifest no or mild symptoms and, after recovery, how they will fare if re-infected. So much remains unknown.

Watawinegi Consup (EC)
Watawinegi Consup (EC)

What is your opinion concerning claims that this is all an elaborate hoax designed to bring the USA under martial law?

JC Onabike

Admittedly, I have been ‘in the wilderness’ on this one for years, with the writing of Michael Rupert being an important early influence on me.

I am also a Ted Gundersen motivated old school conspiracy guy. If you don’t know who Ted is, then you won’t know how long I’ve been highly skeptical of the PTB.

Although I am very hesitant to jump to extreme conclusions, I get where you are coming from for sure.

We cannot ignore the mountain of evidence that profit and control are usually at the forefront of the response to anything of this nature, even if only to take advantage of what could be a horrible (not likely) accident for profit and control.

It is almost laughable that ‘Epistine didn’t kill himself’ is a meme in our current society. The control apparatus is falling apart, and at least some are finally waking up.

Interesting times.

ordo ab chao
ordo ab chao

Hi, JC Onabike…..

One thing I’ll say is you’ve sure got lung…..when I hear ‘bike’, I think one with a motor.

IMHO, what a person believes says much about their motivations, not meaning to point at your motivations so much as to others. You mention T. Gundersen and I kinda view Ted as just a doorman at the mouth of the rabbit hole that is the U.S. Government !

I watched the erroneously labeled Part 1 shortly after MG posted this article, had a few questions but no time to address them…..

I’m about 15 into the video displayed in the article, here is an interesting spin on a possible delay in recognizing this as a pandemic (i posted this link on another thread here):

Is Wall Street Behind the Delay in Declaring the Coronavirus Outbreak a “Pandemic”?

What are your views on transhumanism ? Singularity? Nanotechnology ?

Another link I posted here, with no discussion ensuing, contains this exert:

“Advancements in human genome sequencing, gene editing technologies, and other ancillary sciences (such as nanotechnology) have been instrumental to improving understanding and targeting of genetic mechanisms involved in several organisms’ structures and functions. In 1990, the United States initiated the Human Genome Project. By 2004, a draft had been completed of a significant sequence of the human genome.5 This knowledge was paired with the use of genome-wide association studies that can determine if any variation or mutation is associated with specific traits (for example, a disease or physiological function).6 Taken together with other genetic and genomic approaches, such emerging methods and tools have afforded the ability to identify and affect genes that are associated with or contribute to structure, functions, and abnormalities of the nervous system (that is, neurogenetics). This progress in neurogenetics has led to growing consideration of such assessments and modifications for use in WINS applications.”

https://www.eurasiareview.com/03022020-redefining-neuroweapons-emerging-capabilities-in-neuroscience-and-neurotechnology-analysis/

annuit coeptis novus ordo seclorum <<——-== the goal is the ultimate in chimeric achievements….

I gotta bounce, JC. I'll finish listening to the last half of your 'third' video….

22winmag - TBP's top-secret Yankee Mormon

The USA has been on lockdown since 1871.

We’ve been watching the Democrat crime party.

Watching and allowing the Democrat mob party to incriminate themselves on paper since before the 1910 midterm wave and dirty 1912 election which gave the USA the FED and WWI.

View post on imgur.com

Watawinegi Consup (EC)
Watawinegi Consup (EC)

What is your opinion concerning the Pope’s infection, do you think it is possible the Chinese woman who grabbed his hand on New Year’s eve was infected herself? I wonder what happened to her? How many people might have been infected since the time the Pope was contagious but asymptomatic?

Vixen Vic
Vixen Vic

That’s an interesting question. I didn’t realize the woman that grabbed his hand was Chinese.

mark
mark

Yea, from the vid she had a young ching chang chongette yellow fever…Asian contagion…Delta Phi Omega possibility???

Vixen Vic
Vixen Vic

I never watched the vid, just looked at the headlines. Very good observation.

Cheeto Bandito (EC)
Cheeto Bandito (EC)
Vixen Vic
Vixen Vic

I watched it this time but it’s no help. I can’t tell the difference between Chinese or Japanese. She could be from Taiwan or Vietnam for all I know.

mark
mark

VV,

Yea, I once had a Nà Sản tell me we (American whites) all look alike to her…and I was a short, husky, 165 lbs. black haired mick/wop standing next to a tall, fair, 220 lbs. blond haired Scandinavian guy.

Go figure.

Vixen Vic
Vixen Vic

So it’s not just blacks that all look alike.

Vixen Vic
Vixen Vic

I should have indicated I was being sarcastic.

Vixen Vic
Vixen Vic

I’ve also become a Muppet.

Vixen Vic
Vixen Vic

By the way, is that Tampa Red beside me with the guitar?

Vixen Vic
Vixen Vic

Sounds like it will be hilarious. Can’t wait to see it.

22winmag - TBP's top-secret Yankee Mormon

“And blessed are the Gentiles, they of whom the prophet has written; for behold, if it so be that they shall repent and fight not against Zion, and do not unite themselves to that great and ABOMINABLE CHURCH, they shall be saved; for the Lord God will fulfil his covenants which he has made unto his children; and for this cause the prophet has written these things.”

TampaRed

wasn’t it a jap woman?
but it is a good question–
btw,don’t think i didn’t see your little jab at me the other day–when the time is right …

Cheeto Bandito (EC)
Cheeto Bandito (EC)
Goofyfoot
Goofyfoot

“History shows again and again how nature points out the folly of man.”

James
James

Godzilla!

I will watch video when I have a little more time,then,if I have ?’s will post em,figure the video may already have answers,thanks for your work Jay and TBP,will in future make a contribution but do not do checks and have been banned from the “pal” for firearm related product purchases,so,money order again it is but the lines at me post office usually insane, need to find a slow post office in me region!

Watawinegi Consup (EC)
Watawinegi Consup (EC)

Jimbo, as I recall, Godzilla was awakened from his/her slumber under the sea by nuclear explosions. Godzilla then came to Tokyo and acted super pissed, tore up a few neighborhoods, tangled with some above ground power lines and showed everybody who’s boss. Then Godzilla went back for a nap but always returned just in time to kick some Mothra and Mechagodzilla ass. Reminds me of Stucky.

Two if by sea. Three if from within thee.
Two if by sea. Three if from within thee.

Thank you immensely, MG
JC…I was taken aback a tad at you questioning WHY anyone would work on something like this. I am of the opinion that all agencies, etc, PINE, YEARN for their own personal “Moonwalk”. It is just what mankind does.
Stay safe, be smart and God bless.

RiNS

After reading in the prelude that you believe this 2019 nCov strain was released from a Wuhan Lab a couple of questions pop to mind..

If you could give us a coles notes version of links provided that would be great..

Thanks for posting on this board

1.
What evidence is available that proves the Wuhan Lab was behind release?

2.
Is there biological evidence from examining the genetic information embedded in virus that it is related to the Virus allegedly brought to Wuhan from Winnipeg last year?

Did Chinese Scientists Steal the Coronavirus from a Winnipeg Lab?

Cheers and with Grace of Odin,

RiNS

TampaRed

rins,
is it an undisputed fact that the chinese scientist & her team were fired from the lab?
there is so much bs on the internet that i’ve never been sure about that story–
if true,is it possible that western intel agencies inserted mutations into the virus so that it affected asians worse than non asians–

on the other hand,the link that vic posted last night about this being tb,not a virus,was quite convincing also–

Vixen Vic
Vixen Vic

So far I’ve only gotten to this point in the comments so if the article I posted yesterday has already been re-posted on the thread, I apologize.

J.C. on a Bike and Mr. Big House, I would like for you to read this article by Dr. Bill Sardi, who indicates this “virus” could actually be a strain of TB and the virus itself is simply a rider in the storm. Indicating there is misdiagnosis going on. Please read and let us know your opinion.

Trump Halts CDC Fearmongering. But Why Are Antibiotics & Not Anti-Virals Quelling the COVID-19 Coronavirus? Is It Really a Virus?

Mary Christine

Thanks, Maggie! Now I have two things I can listen to while I drive around this afternoon. I tortured myself by listening to the Senate grill Dr Fauci and others this morning while I did some chores.

I’ll summarize: Big Pharma is the answer and we have to find a way to stop the misinformation and conspiracy theory that this is a bio-weapon going around on the interwebs. You know what that means, dontcha?

I’ll be back this evening to read some questions and answers and maybe I will have some of my own that no one has thought of..or not.

Oh, and thanks, J.C. and Dan.

Watannegi Consup (EC)
Watannegi Consup (EC)

Kinda makes you sad for Pharma Dude, he coulda been a contender selling HIV drugs at sky high prices to corona victims.

the cheese stands alone
the cheese stands alone

did CGTN just pull the plug?

Watannegi Consup (EC)
Watannegi Consup (EC)

no

the cheese stands alone
the cheese stands alone

did CGTN just pull the plug?

Old Timer
Old Timer

Thank you MG! Watched the video and I appreciate what this man had to say. Great job!

Doc K
Doc K

Thank you for posting this! I’m trying to keep up with all the news while I watch “the map.” It looks to be spreading and in my mind the next 30 days here in the US will show how widespread this will be. Virulence is always my question and then how this will affect shipping and economics. Depending on where you live you need to have an awareness of how your “stuff” gets to your supermarket. That’s a long path for me. Situational awareness. Plan accordingly.

M G
M G

Thanks.. am hoping JC and Harvard continue what they do…independent research and discussion.

Peace out.

Doc K
Doc K
Vixen Vic
Vixen Vic

That’s some very healthy stuff right there.

Lars
Lars

“Below is the “first” video: J.C. on a bike, Coronavirus Part I. https://www.youtube.com/watch?v=YL7c-vck4vk&t
J.C. g”

MG, I just watched this video. J.C. says near the begining that this is Part 2, not Part 1.

He goes into a fair measure of detail as to why he has ditched his first hypothesis in Part 1 and concludes that the most likely explanation, at least for now, given what geneticists know and how they typically work along with the fact that RNA, rather than DNA , forms the genetic structure of the Covid19, is that the virus occurred naturally or in the “wild.” Whether it may have been discovered and then “mined” for research or other purposes is another question.

Anyway, I’m not sure why, but the Part 1 video seems to be dated 29 Feb, whereas Part 2 is dated 22 Feb.

22winmag - TBP's top-secret Yankee Mormon

Lots of face masks on Super-Tuesday today in filthy Quincy… aka Chinatown… aka Wollaston area Quincy, MA.

The Corona-Virus cover story is losing steam.

THE KRAKEN IS UNLEASED:

https://imgur.com/OUXVJx4

View post on imgur.com

ILuvCO2
ILuvCO2

Bad on your for being in Mass. What happened to NH. I don’t give a flying fuck about Massachusetts or whatever.

TampaRed

speaking of super tuesday,according to the headlines biden is kicking booty–

Vixen Vic
Vixen Vic

Children’s, I assume.

TampaRed
ILuvCO2
ILuvCO2

OK

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