Ivermectin and the Virus

Guest Post by David Archibald

The efficacy of a drug has not been proven until the journal Nature has run a hit piece attacking it. For ivermectin, that was on 20^th October, 2020.  So many people in South America are using ivermectin now that it is hard to recruit people for clinical trials on the virus.

Ivermectin was discovered in the late 1970s, in a program that tested thousands of soil samples around Japan. A sample from a golf course produced a molecule called avermectin, of which ivermectin is a synthetic derivative. It was approved for human use by the FDA in 1987, and has cured hundreds of millions of people from parasitic worm infections. It is also used to treat worms in farm animals, dogs and cats. Ivermectin is quite benign, with an 18 hour half-life in the body and a wide therapeutic window.

In April this year, a research group at Monash University found that ivermectin inhibited the Wuhan virus in vitro. So doctors in many parts of the world, for the want of anything at all to treat their patients, started using it — with good results.

A recent clinical trial of ivermectin in the Argentinian hospital system produced spectacular results. The study, formally titled “Usefulness of Topic Ivermectin and Carrageenan to Prevent Contagion of COVID Among Healthy People and Health Personnel” had a start date of June 1, 2020 and an estimated study completion date of August 10, 2020. The study team recruited 1,195 health professionals, of whom 407 received no treatment and 788 received self-administered ivermectin oral drops and an iota-carrageenan nasal spray five times per day over a 14 day period. Carrageenan is an emulsifier extracted from red seaweed.

The Argentinian study team reported that the study data revealed that of the participants in the control group (those not taking the study drug combination), 58% of the participants were infected with COVID-19 during the duration of the trial. The study team reported no contagions were recorded in the carrageenan and ivermectin arm. So the result was 58% out of 407 not taking ivermectin became infected while nobody in the 788 people taking ivermectin were infected with the virus.

The same result was achieved in an informal experiment in a French nursing home which was having an outbreak of scabies. Ivermectin was prescribed to all residents and staff of the nursing home. While there were widespread casualties in nearby nursing homes, no deaths or severe cases of COVID-19 occurred among the residents and staff of the nursing home with the scabies outbreak.

Molecules with good anti-worm and anti-viral properties also tend to have anti-cancer efficacy. So it is with ivermection, which has IC50s of 8.1 µg/ml against the breast cancer cell line MCF-7 and 9.1 µg/ml against the breast cancer cell line MDA—MB-231. Work using ivermectin on tumours induced in mice produces results similar to this:

This figure shows the diverging fates of mice injected with the breast cancer cell line MDA-MB-231-GFP. The circles are the control group with no ivermectin and an increasing tumour burden. The squares represent mice being treated with ivermection.

It is almost a year since the Wuhan virus came to the attention of the public in the Western world. In the US, what was engineered as a bioweapon has produced a result like a big and persistent flu season, as shown by excess deaths for the four years 2017 to 2020:

Some countries, such as Sweden, chose to go to herd immunity and did it relatively costlessly. The United States tried to eliminate the virus and will end up with herd immunity at great expense. The various vaccines could make a difference, but will have the same effect that Tamiflu had on the flu. Ivermectin will give a similar result, but far more cheaply and effectively.

Australians are suffering many indignities in the country’s futile attempt to eliminate the virus. Even if that was possible, we are surrounded by countries that will forever be reservoirs of the virus. We would have to turn into a hermit kingdom like North Korea for that to work. North Korea is currently shooting people crossing the border from China because of the possibility they may be carrying the virus.

Ivermectin’s results have shown that nobody has to die from the virus. If you want to prepare for the inevitable but don’t want to get a script for it, there are plenty of choices available from the veterinary trade:

Keep it in the freezer to extend its life and calculate your dosage from your weight. Given that long half-life of 18 hours, daily dosing should do it.

David Archibald is the author of The Anticancer Garden in Australia

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