“Taking antidepressants is as risky as taking recreational drugs”

UCL Professor of Psychiatry Joanna Moncrieff interviewed by Torsten Engelbrecht

Torsten Engelbrecht: Dear Joanna! You say that your recent study, in which you suggest the prevailing hypothesis that depression is caused by decreased serotonin activity or concentration is baseless, “has caused shock waves among the general public“. Why?

Joanna Moncrieff: People believed that there was scientific evidence that demonstrated a link between serotonin and depression. And people have believed that because in the 1990s, the pharmaceutical industry launched a very widespread, heavily funded promotion campaign to persuade people that depression was due to a chemical imbalance and specifically a lack of serotonin, which could be rectified by taking an antidepressant.

That was a huge marketing campaign that was aimed both at doctors, but also at the general public via the internet. And in countries that have direct to consumer advertising, it was directly advertised to consumers on television and radio and other media. And that was very successful.

That campaign was launched in order to counteract people’s underlying common sense feeling that taking a drug for an emotional problem was probably not a good idea.

And that campaign has successfully reversed that idea and replaced it by this belief that depression has been shown to be a chemical problem, which it turns out is not the case. It turns out there is not evidence to support that.

TE: But your criticism actually is not really new. Psychiatrist such as David Healy or Peter Breggin expressed exactly this criticism already years ago. So why does this criticism not reach the surface of reality?

JM: Leading psychiatrists have known for a long time that there was no evidence to support the serotonin theory of depression. But no one has informed the general public of that.

No leading psychiatrists have taken it on board to let the public know.

People like David Healy have, and people like myself and some other people have written about this. The leaders of the psychiatric profession, we have to conclude, have been happy to allow the general public to continue with this misperception that a link between serotonin and depression had been established.

TE: But there’s also contradiction. Ronald W. Pies, for example, professor emeritus of psychiatry counters regarding your review that“historically, psychiatrists have never explained clinical depression solely in terms of reduced serotonin or any specific neurotransmitter“ and as with selective serotonin reuptake inhibitors, so called SSRIs such as Prozac, “many drugs in clinical medicine work through unknown or multiple mechanisms. And this does not affect their safety, efficacy or approval for medical use“.

Doesn’t this contradict your views?

JM: There are a couple of points there that you’ve made. First of all, it is true that psychiatrists have always seen depression as a bio-psycho-social phenomena where the biological is only a part of it.

But there is a problem. If you suggest that there is a specific abnormality in the brain that can be targeted by a drug, then obviously it makes sense to take that drug. Especially if you suggest that other things such as what’s going on in people’s lives are downgraded to a second place and focus on a problem in your brain, then obviously you need to correct it if you can correct it.

But this approach is misleading because to suggest or to tell people that an abnormality had been established, that an abnormality of serotonin had been found has no scientific basis because in fact it hadn’t been found.

You are also right that many psychiatrists have recently been saying that it doesn’t matter how antidepressants work and that these psychiatrists haven’t necessarily been saying that the drugs work by rectifying an underlying chemical imbalance.

There are two points I’d like to say to that. First of all, it really does matter how antidepressants work. And secondly, even if psychiatrists haven’t been promoting the idea of the chemical imbalance, because it has been so widely absorbed and because so many people believe it is established, it’s not good enough to just not promote it.

You actually need to tell people that it is not supported, that there is no evidence for it.

TE: The most important evidence would be a placebo controlled study showing that taking an antidepressant would be much better than doing nothing.

And in this context you say that studies show that antidepressants are only “marginally better than a placebo [or inaction] at reducing depression scores over a few weeks. However, the difference is so small that it is not clear it is even noticeable and there’s evidence that it may be explained by artifacts of the design of the studies rather than the effects of the drugs.“

But I’d like to quote Pies again who counters that “there’s ample evidence from placebo controlled studies that serotonergic antidepressants are safe and effective and the treatment of acute major depressive episodes.“

JM: This is really important. So many people have been saying in response to our paper, that antidepressants work, that they’ve been shown to have important and substantial benefits.

And I would respond to that, that I don’t think that that is true. There have been many large analyses of antidepressant placebo controlled studies that show that the difference between the placebo and the antidepressant is very small. There’s no debate about that.

There’s been a very large study published recently in the journal BMJ. And what it shows is the difference between the antidepressant and the placebo on the depression rating scale score is less than two points on a 52 point scale.

No one thinks that difference is clinically significant. And the other thing is that these trials are all short-term. And as you mentioned, there are lots of other methodological reasons that actually might inflate these differences.

So that small difference may not even be a real difference.

The issue is that if you compare antidepressants with placebos in trials there is a little bit of difference. And the question is what is that difference due to, and I think there are two possible explanations here.

One is that in these trials, people often know whether they’re taking the active drug or the placebo, because they can tell they’re getting a few side effects. They feel a little bit different. And so the people on the active drug in these studies may well be getting what we could call an “amplified placebo effect.“

And that could be the explanation for the difference between the placebo and the drug.

The other possible explanation is that antidepressants have this emotional numbing effect. And so that could be temporarily reducing the intensity of someone’s underlying sadness and feelings of depression, as well as reducing the intensity of any positive feelings that they have, like happiness or joy.

TE: If science is clear that there’s no solid study showing that taking an antidepressant is better than doing nothing or taking a placebo, the why there are people such as Pies still defending the official line?

JM: Psychiatrists appear to be very reluctant to overly criticize antidepressant use. And I think that’s because the psychiatric profession and much of society following their lead has become convinced that depression is a medical problem that can be addressed with a medical solution. And therefore they feel threatened by anything that fundamentally questions that narrative.

TE:: How much influence does the pharmaceutical industry have on psychiatry?

JM: The pharmaceutical industry has been very influential on the public and influential on the psychiatric profession. But we also need to remember that actually the psychiatric profession came up with this idea of the chemical imbalance before this pharmaceutical industry had really got that involved because the theory that depression is related to low serotonin goes back to the 1960s and was proposed by a British psychiatrist.

The pharmaceutical industry really gets into promoting this idea of the chemical imbalance in the 1990s. So they certainly reinforce the idea among the profession of psychiatry, but what they really, really achieve is persuading the public that this is a credible theory that has been established.

TE:: Is there any major study not being financed by the pharmaceutical industry, is there any independent science?

JM: The pharmaceutical industry have massively influenced research on antidepressants because they conduct the vast, vast majority of the studies on antidepressants.

And we know that pharmaceutical industry studies often “inflate“ the effects of the drug that the pharmaceutical company is promoting. If the studies don’t show a positive finding for the company’s drug, they are not being published, they are “buried“.

And even in studies that get to publication often they’ve been tweaked, they’ve been “massaged“, positive outcomes are highlighted more than they reasonably should be.

So, yes, the pharmaceutical industry has definitely had a substantial influence on the research into antidepressants.

TE: I’d like to quote the psychiatrist Pies again who also states that if serotonercic agents are not helpful, antidepressants from other classes may be considered“.

In contrast the US journalsist Robert Whitaker, for example, who is critical of today’s drug fixated psychiatry for many, many years, told me in an interview in 2013 “If you look at how the drug cocktails are prescribed, it’s all really a bit of witchcraft“ in the sense of mumbo jumbo.

So can switching for other medications be a solution – and if so, is there hard evidence that this approach is useful? Or is all this really “witchcraft“ as Whitaker says?

JM: We showed there was no evidence to support the idea that antidepressants might be rectifying an underlying serotonin abnormality.

There is no evidence and there is no better evidence of any other abnormalities of other neurochemicals that might justify the use of antidepressants that work in other ways.

All antidepressants are psychoactive substances in the sense that they change normal mental states. So a lot of antidepressants are reported to, for example, produce a state of emotional numbing, numbing of both positive and negative emotions.

And these are effects that of course are going to impact depression rating scales and other measures that are conducted in randomized trials.

And all antidepressants will affect people, will change people’s normal thinking and feeling in one way or another, or although some of them have very subtle effects.

All sorts of antidepressants do have effects on people, they are not simply „inert“, inactive substances. But we have no evidence that what they are doing is targeting the abnormality that lies underneath depression, or that causes the symptoms of depression, whether it’s a SSRI or another sort of drug.

Many people report that they feel better after taking antidepressants, and many, many people do feel better after taking antidepressants. We know that many people also feel better after taking a placebo.

We know there is no doubt that the majority of the effect of an antidepressant is a placebo effect. The effect of people’s expectations and of being offered hope and support is huge. That has a substantial effect on people’s outcomes.

TE: You also say that “it is not self-evident that manipulating the brain with drugs is the most useful level at which to deal with emotions. This may be something akin to soldering the hard drive to fix a problem with the software.“

It sounds as if you are criticizing the mechanical way of thinking of today’s times that dominates the modern world and to which the French 17th century philosopher René Descartes contributed significantly.

He considered the body of living beings as a kind of a machine. But aren’t the event in the body far too complex to be compared to a computer hard disc that you repair by soldering something? And where does that leave room for dealing with emotions or feelings?

JM: We need our brain and our body as well to think, to feel, to communicate, to do everything that we do. But that doesn’t mean that we can explain the nature of our thoughts and feelings by looking inside the brain.

It’s the wrong level at which to understand human behavior, human thoughts, and human feelings in my view and in the view of many other people who criticize this reductionist view that you can reduce depression or happiness or love or someone’s political views, someone’s taste of books or music to events in the brain.

Many philosophers have written about how this view is nonsensical. These human attributes like love and appreciation of music need to be understood in the context of the human world.

They make no sense if you try and talk about them in terms of nerves and neurological events and activity.

TE:: Even experts such as Pies concede that “there is legitimate debate over the efficacy of long-term anti-depressant use“, while you not only say that it is “impossible to say that taking antidepressant or SSRIs is worthwhile“, but also that “it is not clear that these drugs do more good than harm“. What harm can they do?

JM: This is a really important point. If we have no evidence that antidepressants are working by reversing an underlying abnormality – and we know, and no one denies that, that these are drugs that work on the brain – we have to conclude that these drugs are actually changing the normal state of the brain.

They are modifying it, they are altering our normal brain state, our normal brain chemistry. And if you take a substance that alters your normal brain chemistry every day for weeks and months and years, you may do yourself some harm.

We know that because we know that people who drink a lot every day cause themselves harm and people who take other recreational drugs that also change brain chemistry can do themselves harm.

And we know that taking antidepressants in the long-term can cause a number of harms that relate to the way they modify the brain.

For example, we know now that people become physically dependent on antidepressants and therefore when they try and stop them, they can experience really sometimes quite severe and debilitating and prolonged withdrawal symptoms.

We also know that antidepressants cause sexual dysfunction. They do that even in the short term. And it’s a very common side effect, very well recognized. But it’s becoming increasingly clear that in some people the sexual side effects persist when people stop taking the antidepressant.

And that implies that the antidepressant has changed the brain in some way, in some harmful way.

I’m not saying that this is necessarily a permanent state. We haven’t recognized this effect for long enough, really to know whether it is persistent or permanent or whether it might go away with time. But it’s definitely something that seems to happen to some people who have been using these drugs for long periods of time.

TE: Antidepressants have also been linked by experts such as Peter Breggin as a cause of violent acts and even homicides. What do you think about that?

JM: The evidence suggests that antidepressants can cause younger people to engage in suicidal behavior, more often than people on a placebo. This is evidence from randomized controllled trials.

There is also a higher risk of aggression in young people taking antidepressants compared to young people in these studies who are taking a placebo. The risk in these studies is very small and it’s only in younger people.

The risk is small partly because these studies are trying to select people who don’t have any preexisting risk factors or have a minimum number of preexisting risk factors.

So in real life, the risk actually might be a bit higher. I think that this risk is related to the fact that antidepressants seem to have an agitating effect in younger people in particular. And we don’t know why this happens more in young people than older people, but it does seem to.

So in younger people antidepressants can make someone more agitated, tense, irritable, and emotionally labile. And that effect seems to be related to impulsive behavior which might include self-harming, suicidal and aggressive behavior on occasions.

TE:You also say that „only a minority of medical drugs target the ultimate underlying cause of a disease“. So what would a treatment for mental illnesses like depression look like that addresses these „underlying causes of a disease“?

JM: Medical drugs may not treat the underlying cause of the disease. Most of them don’t, but they do target the underlying pathways, underlying biological pathways that produce symptoms. So even painkillers, which are clearly only a symptomatic treatment, target the underlying neurological mechanisms that produce pain.

Psychiatric drugs work differently. They’re not targeting any underlying processes. They are producing alterations to normal mental states, which are then superimposed onto whatever emotional problem the person is experiencing.

At the moment we don’t know and we have not identified any underlying neurological processes for any sort of mental disorder that could be targeted by a biological treatment. And I’m not sure that we will be able to do because I think that that the view of mental disorders is inappropriately reductionist.

I think that is the view that is trying to find the problem in the brain, rather than looking at the problem at the level of the human being and the human being in her world.

TE: What does this mean for the use of drugs? As I mean, does Peter Breggin, for example, triy to avoid using antidepressants in general. What about you?

JM: If people are feeling depressed and they take a drug, I think you need to see it in the same way as taking alcohol. It changes your mental state temporarily while you were taking it, and then you stop taking it. And the mental state comes back.

And if you’ve been taking the drug for a long time, possibly you get some other complications as well.

So in general, I think that drugs should be avoided and particularly avoided over the long term.
I think there are some crisis situations where a drug such as Benzodiazepine which relaxes people, helps people get to sleep, can be helpful for a few days.

The most important thing for me is to really give people information so that they can make up their own minds about the use of drugs.

And there may be some people who feel that they want to try and change their normal mental state and they want to feel different and they want to numb their emotions.

And then we need to have a debate about whether we think that’s an appropriate medical treatment for emotional problems, whether that’s something that we should be facilitating or not.

But the first thing to do is to be really honest about what is happening when people are taking drugs to deal with their emotional problems and to involve patients in that debate.

TE:What is the alternative then? It’s doing psychotherapy for example, or what about things like sports and nutrition and toxins such as heavy metals?

The book Nutrition and Psyche, for example, whose first edition is from the 1980s, deals with the influence of nutrition, but also of industrial toxins on psychological wellbeing.

And in 2021 the study“Diet, exercise, lifestyle, and mental distress among young and mature men and women” concluded that “our results support the need to customize dietary and lifestyle recommendations to improve mental wellbeing“. Is that an approach you think that should be supported?

JM: So the first thing I would say is that I think we need an approach that starts to see mental health problems differently. So instead of seeing them as diagnoses or disorders that are the same in everyone who has them, we see people as individuals who have their individual set of problems. And every person with depression is responding to a different set of circumstances.

And it’s understanding why someone is depressed and what the circumstances are that have made them depressed. That is the most important thing in helping someone. So each person with depression needs a different solution, depending on what has made them depressed.

If you are depressed because you are having relationship problems, you may need some relationship counseling, you may need a dating app. You may just need a friend to have a cup of tea with and to cry with now.

Again, you know, it’s going to be different for everyone.

That’s the first thing: Everyone has mental health problems for different reasons. And it’s the reasons why people are having these problems that we need to focus on rather than giving people blanket treatments.

Having said that there are some sensible things that people can do to improve them emotional and mental resilience. And one of those is definitely exercise. Exercise has very good effects on mood and on reducing anxiety.

So I think exercise is really important for people. The same holds for eating well, eating a good balanced diet, and just looking after yourself. Making sure that you have enough sleep is another really, really crucial factor for general mental wellbeing.

I think all those things are important. I’m not sure that I want to go down the root of any particular diets or dietary supplements or anything like that. But I think certainly that looking after yourself, doing lots of exercise is definitely going to be helpful.

TE:What should people affected do then? Are there even many therapists who would not drive a drug fixated approach and would be at least willing to abandon on a patient’s request or do let’s say 99.9% of the psychiatrists follow the drug fixated pathway?

JM: Most people are prescribed antidepressants by their general practitioner rather than by a psychiatrist. And I know that general practitioners are trying to offer people alternatives.

So I think that we need a combination of a public information campaign to inform people that this idea of the chemical imbalance was wrong, was not supported and that we don’t know that antidepressants are working in this way and they could be doing something quite different, which has some worrying implications.

And we need to educate doctors, we need to encourage and support doctors to offer patients alternatives to medication such as subscriptions for the local gym.

In the UK, we do have a certain amount of „social prescribing“ whereby doctors can give people gym prescriptions or recommend other social activities for people instead of giving them and prescribing them medication. And we need to support and promote that.

TE:What made you becoming critical – and is it difficult to be critical in your profession or do you get a lot of support as well?

JM: I developed a critical attitude towards psychiatry and traditional medical solutions to psychological problems when I was a trainee, because although other people seem to feel that psychiatric medications like antidepressants worked I really couldn’t see that.

Yes, some people got better, some people got worse. But when people got better, there seemed to be another explanation. It didn’t necessarily seem to be tied to the drug in my view.

So I wasn’t convinced. I developed an interest in psychiatric drugs and started looking at the literature in detail. And then it became obvious that there were lots of methodological and conceptual problems in the research on psychiatric drugs and psychiatric disorders.

I was also aware that some of my fellow psychiatrists shared my concerns about the dominant biomedical approach to mental health problems.

And for that reason, I set up a little group called the Critical Psychiatry Network, which is still going and which consists of psychiatrists like me who have a skepticism towards the biomedical model and a skepticism of the dominance of the pharmaceutical industry and the dominance of medication centered approaches for mental health problem.

TE: What about the whole profession you’re working in, how does it react to your views? Are you only a small group, are you the exception?

JM: We are a minority group and probably most of the leading figures of the profession are people who have an interest in biological psychiatry and have been doing biological research and worked with the pharmaceutical industry. But there are some social psychiatrists who are more focused on the social causes of mental illness and also on social treatments and service configurations. And certainly there are lots of social psychiatrists in the United Kingdom…

TE: …But you’re not under attack or under pressure from, from colleagues or whatever?

JM: There are social psychiatrists and there are people like me, but there is still a great deal of defensiveness, I would say, in the psychiatric profession, particularly when you start to question the basis of drugs like antidepressants that are so widely used.

So yes, I’ve been criticized for speaking out about this paper and for trying to highlight, particularly for trying to highlight the implications that it has, that this research on serotonin has for our understanding of the use of antidepressants.

I do feel that the profession would rather that this subject is not debated in public and would rather that people are not aware of the fact that antidepressants are mind changing and brain changing drugs that may have harmful effects if they’re taken for long periods of time.

TE: Let’s have a quick look into the future: Are you confident that this is gonna be changed or what do you think?

JM: Oh, Gosh! I think there are many people now, especially when I speak to people in the USA, who are utterly convinced that mental health problems are problems in the brain and that we just need to treat the brain and we need to find the right drug or the right sort of biological intervention. That attitude has taken very deep root in the public consciousness in the last few decades. So I don’t see that changing overnight. On the other hand, there are also significant numbers of people who are starting to question that idea. And I think and I hope that those numbers will increase after the publication of our paper and due to debates, like the one that we are having now and that you’ve had with other psychiatrists, other critical psychiatrists and critical voices in the mental health field.

TE: Thank you Joanna for this conversation. I wish you all the best. And thank to all the viewers for watching us. Hope to see you next time again.

JM: Thank you, Torsten

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43 Comments
Anonymous
Anonymous
October 3, 2022 9:43 pm

Ever see all the anti depressant commercials? Always depicting and aimed towards white women. All the rest of pharma commercials are minorities.

YourAverageJoe
YourAverageJoe
  Anonymous
October 3, 2022 10:43 pm

Yes.
You will see.more.and.more.White hatred.

Dr. Zedder Strangelove
Dr. Zedder Strangelove
  YourAverageJoe
October 3, 2022 11:34 pm

Whites are not fit for purpose. Genetically suicidal.

The Central Scrutinizer
The Central Scrutinizer
  Dr. Zedder Strangelove
October 4, 2022 3:34 am

Fuck you, you racist asshole.

Dr. Zedder Strangelove
Dr. Zedder Strangelove
  The Central Scrutinizer
October 4, 2022 3:51 am

Yes, I am . Truth be told, I do not in general like the human race. I don’t see any hope for us. Yes there are some super smart ones. But we need another step or two to move forward as an intelligent species in the cosmos or with any meaningful duration.

Dr. Zedder Strangelove
Dr. Zedder Strangelove
  Dr. Zedder Strangelove
October 4, 2022 3:56 am

I would rather AI robots(Borg) make it off the planet because at least their hearts not in the insanity that ensues from their being. Humans put all their heart into being as crappy as they can be most of the time.

The Central Scrutinizer
The Central Scrutinizer
  Anonymous
October 4, 2022 3:46 am

You actually WATCH the commercials?

Shit. THAT’S WHY you’re depressed!

Anonymous
Anonymous
  The Central Scrutinizer
October 4, 2022 6:33 am

I watch advertising to analyze it. I’m not a tv person really. I’m not depressed myself.

The Central Scrutinizer
The Central Scrutinizer
  Anonymous
October 4, 2022 11:44 am

That’s OK. I’ll be depressed enough for both of us.

Anonymous
Anonymous
  Anonymous
October 4, 2022 6:14 am

In the 1960’s the consumer establishment with the help of government, cultivated the idea that pills can enable a do-anything existence. Do what one wants and take a pill to make it all possible.

flash
flash
  Anonymous
October 4, 2022 6:39 am

Give ’em some happy pills and let ’em vote, bruh…that’s muh democracy, right there.

comment image

Anonymous
Anonymous
  flash
October 4, 2022 8:29 am

Give ’em some happy pills and let ’em vote, bruh…that’s muh democracy, right there.

Winner, winner chicken dinner!!

Dr. Zedder Strangelove
Dr. Zedder Strangelove
  Anonymous
October 4, 2022 11:15 am

Nuff said.

TampaRed
TampaRed
  flash
October 4, 2022 9:42 pm

“1 out of 4 american women are on psych drugs.”
3 out of 4 should be–

Dr. Quackula
Dr. Quackula
October 3, 2022 10:05 pm

There is no chemical imbalance. Depression is caused by brain damage due to bad parenting, schizophrenia is caused by a virus and manic depression is a left over from inbreeding.

YourAverageJoe
YourAverageJoe
  Dr. Quackula
October 3, 2022 10:45 pm

But as an Anominous person observed, it seems to magically affect White women, at least in the teevee commercials I’ve seen.
It is my experience that Hispanic women are given to psychosis every bit as much as White women because I have been married to both.

Anonymous
Anonymous
  YourAverageJoe
October 3, 2022 10:53 pm

My point was that these drugs are pushed towards white women more.

Dr, Quakula
Dr, Quakula
  Anonymous
October 4, 2022 12:15 am

Statistics don’t lie, rates of mental illness are 40% higher in Ashkenazi Jewish and Muslim communities due to inbreeding. For centuries these groups married first cousins. Schizophrenia is caused by a viral footprint likely the result of a vaccine. The NIH has found evidence of this. The first case of Schizophrenia appeared at the same time as the first mass vax campaign for smallpox. Depression like I said is mental damage cause by bad parenting. Show me a depressed person and I will show you a person with a dysfunctional or abuse upbringing.

And yes, meds are directed at neurotic white women.

Anonymous
Anonymous
  Dr, Quakula
October 4, 2022 11:28 am

There may be a genetic component to schizophrenia, or you may be right about it. I don’t know.
What I do know is that you are 100% correct about depression, as well as anxiety and a whole host of mood disorders and even personality disorders.
The chemical band-aids by which psychiatry now perpetuates itself are, in the long term, more harm than help.

Tim
Tim
October 3, 2022 10:30 pm

So, recreational drugs it is, then?

The Central Scrutinizer
The Central Scrutinizer
  Tim
October 4, 2022 3:40 am

Ty (Chevy Chase) – Do you do drugs, Danny?

Danny Noonan – Every day.

Ty – So, what’s the problem?

Caddy Shack

YourAverageJoe
YourAverageJoe
October 3, 2022 10:37 pm

How in the heck did such a brilliant group of Men cobble together the most enduring form of Government, as spelled out in the Declaration and the Constitution ever manage to pull it off without the benefit of anti-depressants?!?!?

I’m an ongoing experiment.to see.how.long a short bald guy like me can live without Modern Pharma’s chemicals in me.

About 20 years ago, I wrote my family tree, and noticed the my ancestors lived just as long as or.longer than my more.modern relatives.
I view that as the consequence of living in a.liar country vs an honest one, rather than the injection of chemical cocktails.

We hold these truths to be self evident…that it is our Right, it is Our Duty to throw off such Government and.appoint new Guards and all that.
When freshman congresspersons like Lizzie Fletcher (D) (district7TX) become millionaires on a congresspersons salary ahead of the arithmetic, you should know George Carlin had the crystal ball the whole time.

The Central Scrutinizer
The Central Scrutinizer
  YourAverageJoe
October 4, 2022 3:43 am

How in the heck did such a brilliant group of Men cobble together the most enduring form of Government, as spelled out in the Declaration and the Constitution ever manage to pull it off without the benefit of anti-depressants?!?!?

Cocaine and alcohol.

TampaRed
TampaRed
  The Central Scrutinizer
October 4, 2022 9:39 pm

george washington’s “hemp” —

Dr. Zedder Strangelove
Dr. Zedder Strangelove
October 3, 2022 11:32 pm

As I read this I can’t help but think of an old screen name I used to see, Serotonnin Dumptruck . These drugs have been given to kids like everyday is Halloween. It is making for some fun times now. If the kids weren’t alright then (grade school) those happy pills certainly haven’t helped now. Your kid needs some drugs to help them concentrate at school, Basically chemically parenting the kids into a stuper so they didn’t have to do actual parenting. Serenity now(mostly for parents) Insanity later(Kids Ball Peening mostly their parents). Withdrawal symptoms are varied and unpredictable, dysregulation is a bastard even months into being clean.

Anonymous
Anonymous
October 4, 2022 6:11 am

I have been banging this drum for 25 years. It is good to see the research. The mental health of the people of the west is now completely fucked up. This is why so many people died of Covid in the United States. We have billions of fat, lonely, depressed people on SSI who died during the lockdown plandemic. All people need healthy eating, exercise, friends, and flow in their lives to survive and thrive. In our consumer and anti-white world, one also needs to take an active stance against the dominant culture and engage in retroculture.

flash
flash
  Anonymous
October 4, 2022 6:47 am

Billions, bruh?

Putin it where it counts
Putin it where it counts
  Anonymous
October 4, 2022 10:39 am

All’s well and good to say except we live in a dystopian hillscape with no economic opportunities a culture being destroyed by global war threat of famine economic destruction and the obvious fact that a government doesn’t care about us a hegemonic ruling class that will never be part of and no opportunity to advance or even thrive

Anonymous
Anonymous
October 4, 2022 10:59 am

Stopped reading after getting the gist of the article. Irritating.
For all the negative press anti depressants get, it’s little wonder the negative narrative is parroted.
Anybody who has first hand experience with depression, and has seen or experienced the upside of it,
as evidenced by the successful emergence from such a dark, commonplace affliction can testify to the positive.

Granted, there are problems some meds cause, particularly for psycho women and vulnerable adolescents,
but, speaking from experience, some people have had their lives saved, with spectacular 180 degree turns,
away from the dark, lonely, utterly helpless feelings of depression, and toward an amazing return to a stable,
promising life, where each day is one that is grateful for the saving grace, and escape from suicidal thoughts.

Each individual who has suffered from severe depression most likely has a unique basket of experiences that
probably causes the affliction.

With all the research that’s been done about it, the ‘experts’ in mental health care still don’t know precisely what causes it.

There are common denominators that are used to compare individual cases.

Some cases are mild, and little more intense than the typical blues that drag people down from time to time.

The severe cases are red flags.
Not to be avoided at all costs, unless the subject is a stranger who deserves no interaction with us.

But if you or a family member becomes afflicted, then patience, support, understanding, and help is vital.

Success stories who have emerged will report, that if emerging was as easy as thinking:
“Snap out of it!. You have so much to be grateful for. There are people who are way worse off than you.”
Well, if it was as easy as throwing a mental toggle switch, that action would have been conducted early on,
when the affliction first rears its ugly head.

That’s the main challenge with the afflicted.
They lose control of the ability to rationally think.
The anxiety thoughts come from who knows where.
Media input, daily interactions, and unfortunate experiences from the present and the past.
The list is endless, for potential stimuli that can trigger it.

Anybody who has never suffered under such agony has very little understanding of the topic,
and has very little empathy for people who are afflicted.
Armchair psychologists, who, because they have their mental health 100% functioning,
often are heartless in their arrogance and cold heartedness toward those who are afflicted.
To them, I say, There but for the grace of God go ye, and your family, brethren, and friends.

The condition still has a stigmatism to it. Shamefully.

If ever so afflicted, either you or a close family member or friend, do more research, and seek
help, and guidance.

Some meds might not work.
Some might also bring nasty side effects.
But, don’t stop trying.

Personally, it took trying a couple different meds, but when one was found that was very helpful,
a life worth saving was turned around for the better.
–> On three separate occasions, I’d add.

What may come easily to you as an individual might be extremely difficult for others so challenged.
Empathy is the ability to envision walking in another’s moccasins for a few miles, before chastising, casting judgments, and condemnation for their weakness.

Strength is a must, for survival in such a chaotic world.
For some, it is as naturally understood as a concept.
For others, it presents a challenge that emits a form of agony that cannot be described easily,
that the unafflicted can relate to.

The condition can be overcome, with effort, practice, support groups, and sometimes with
an anti depressant that is ultimately deemed a miracle, for bringing some folks away from the brink
of tragedy.

Some noble understanding of that is the mark of wiser, more intelligent men and women.

Give those so afflicted a chance. Some help, if so desired. Give them the benefit of your doubts.
You could be helpful in saving a life that is worth living.

You’ll be a better person for it, and so will the person you aim to try and help.

Finally, be advised. It’s not an easy task.
It’s much easier to turn away, and let somebody fight their demons alone, if not your problem.
Keep trying.
Stay with it.

When somebody emerges out the other side of a mental health challenge, God is at work.

Try and be a faithful and trusted servant.

Or not.

Your choice.

Dr. Zedder Strangelove
Dr. Zedder Strangelove
  Anonymous
October 4, 2022 11:22 am

Drugging millions of kids the get to the few legitimate mental health problems is not an answer, nor is drugging children an answer for lazy inattentive parenting, or from social media based trauma. But you are correct in so far as so many people have a myriad of experiences that cause them to forever look back and become negative(depressed). It is so hard(almost impossible) to get anyone to start moving forward positively.

brian
brian
  Dr. Zedder Strangelove
October 4, 2022 8:42 pm

myriad of experiences that cause them to forever look back and become negative(depressed). It is so hard(almost impossible) to get anyone to start moving forward positively.

Like anon stated… you likely have never experienced depression if you think its a matter of just being ‘negative’ and a ‘positive’ attitude will solve the problem. It’s none of that negative positive BS, its entirely, imo, a chemical imbalance somewhere and a spiritual thing. Victims don’t choose to be in those positions. I go thru bouts of sever depression and its usually winters and pain loads that send me over the edge.

I’d give anon 10K thumbs up if I could as everything stated is accurate. Been there do that still… Not something I look forward to and its hell on my family too, which just adds to the pain…

Dr. Zedder Strangelove
Dr. Zedder Strangelove
  brian
October 4, 2022 9:20 pm

No, I hear ya, I spent a lot of time(years) thinking up ways to do myself in. I’ve had a fair bit of screaming on the ground cause max pain showed up. (again years worth) . I found that max physical pain (death like, chainsaw into my body feeling) actually couldn’t be surpassed, Then I was free to move(had to writhe my way to the house before it burned down). Debilitating pain for years, tears would roll down my face as I helped push women out of a snowbank. Pain is a feeling that is not necessarily real or infinite. Cut yourself open and give your nerves a squeeze tell me it’s different than physical trauma. Ones real one isn’t. But they feel the same. I always said fuck you to it. Actually total visceral scream. I’d have to tell people I don’t need an ambulance, while out of control on the ground. And I haven’t even touched some personal shit. I am fully aware how shitty constant pain is. It wears you down and depresses even the most invincible of us. And then for those of us who are lucky, it gets even tougher. I know, and I guess you do too. I never chose to crash my crotch-rocket. And I didn’t ask to be pinned between cars (can’t feel some parts of my leg anymore), and I didn’t ask to be blindsided by a truck(which made my separated shoulder go from stage 3 to stage 5). I didn’t ask for hundreds of stitches in my face. And I certainly didn’t ask to drink thru a straw (burned face)when I was supposed to be on vacation. And it sucks when I have a hard time concentrating and just barely doing the speed limit cause pushing the gas pedal is making it hard to see. But I always say “FUCK YOU PAIN” and make lemonaid if I can. Also shattered my hand, I still play piano. Though not for long. I don’t care how much it hurts. I’m handing in a totally used and already fully damaged body when it’s my time. I am invicible till I’m not. Funny one, broke my arm at school, had to wait an hour, for my mom to pick me up to go to the hospital. When she pulled out of the school driveway and turned, her hot coffee(fresh from home hot) spilled on my broken arm. Haha, we laugh about it still. Today is worse then yesterday, but it’s better than tomorrow.

Dr. Zedder Strangelove
Dr. Zedder Strangelove
  Dr. Zedder Strangelove
October 4, 2022 9:27 pm

Cyclobenzaprine, Celebrex, Gabba pentanol, oxycodone fentanyl ,Etc. T4’s are for kids. Just some of the constant pain meds I had to take for years. Legal ones. Lots o ghosts in my closet. Oh yeah, never said it was easy(it ain’t), but it makes just a good day unbelievably awesome. If you don’thave the want, then pills alone won’t fix you. And drugging ad infinitum doesn’t work. If you just keep looking back, you will never move forward.

brian
brian
  Dr. Zedder Strangelove
October 4, 2022 9:39 pm

All familiar to me… Add hydromorph contin, fentanyl patches, cymbalta(not a pain med but sure fucks the brain)

You know the pain thang…

brian
brian
  Dr. Zedder Strangelove
October 4, 2022 9:34 pm

But I always say “FUCK YOU PAIN” and make lemonaid if I can.

We’re on the same page when it comes to pain. This has been my life for 30+ yrs now. Little sleep, constant pain and I do what you do… I spit and say FU and carry on, push thru… I hide much of it in lame humour…

But depression is another animal altogether. You simply cannot pull yourself up and put on big boy undies and lets go… The best I can describe it is like being in a round room with no lights and filled with syrup and you need to find the exit. You can’t process information, its dark and theres no energy to do even simple tasks. Even talking with family is draining.

I can take the pain and yes its fucks you up seven ways to Sunday on every level you can conceive of. If given the choice I’d take the pain any day over depression… but I don’t have that choice…

Dr. Zedder Strangelove
Dr. Zedder Strangelove
  brian
October 4, 2022 9:51 pm

Sucks eh? Goddamn monkey’s we got, but my point is you have to have the want to keep driving/searching/reaching even when the nuclear oil of blackness is enveloping your entirety of senses. Pills will only get a person so far. You can OD on happy pills and never experience anything other than misery. I wish you luck on your journey. Is all I can say.

Anonymous
Anonymous
  brian
October 6, 2022 1:30 pm

Your brain chemistry at any given moment is determined by your perceptions, not the other way around.

A simplistic analogy:
1. assume looking at a beautiful sunset creates joy
2. assume the feeling of joy = serotonin production
3. does your brain produce serotonin (joy) and that production causes you to look at a beautiful sunset? Or, does your brain produce serotonin (joy) in response to having viewed a beautiful sunset?

The chemical imbalance theory puts effect BEFORE cause. It is illogical.

Your therapist and psychiatrist have never thought of this. They have never thought of this because they DO NOT THINK. They do not question. To question causes problems.
They were taught a lie. They repeat that lie.
You believe them, because you trust them.
That is a mistake.

Anonymous
Anonymous
  brian
October 6, 2022 1:00 pm

its entirely, imo, a chemical imbalance somewhere

No. Wrong.
Provably wrong (as shown in the article).
And ZERO evidence in favor of that view, except the influenced opinion of every psychiatrist and psychologist.

Anonymous
Anonymous
  Anonymous
October 6, 2022 1:11 pm

You have intense physical pain somewhere in your body (let’s say your arm).
You go to the doctor. The doctor immediately shoots your arm with a pain killer and says, “I’ll be back in 5 min when that kicks in” and walks out.
The pain killer kicks in. You feel no pain.
Doctor walks back in and says “Okay, now tell me where it hurts so I can figure out what’s wrong.”
You can no longer tell him where it hurts, thus he can no longer figure out what’s wrong.
Doctor says, “Well, come back in two weeks.”
Wash. Rinse. Repeat.

There may be no cure. There may be no way to identify the source of your pain. However, if there is a way, and there is a cure, you will now never find it because you are constantly separated from your pain.
This makes you an excellent customer.

A patient cured is a customer lost.

You cannot have a cure. You cannot identify the source of your pain.
Not because they don’t exist, but because NO ONE is looking for them.
Why would they?

Lucredius
Lucredius
October 4, 2022 12:00 pm

I’ve never encountered anyone in the mental health industry that did not need mental health care . Including my own Mother!

Dr. Zedder Strangelove
Dr. Zedder Strangelove
  Lucredius
October 4, 2022 12:15 pm

They are forever stuck trying to figure out why they are the way they are. Self diagnosis is never any good, unless your prescribing for self-recreation.

Ken31
Ken31
October 4, 2022 8:17 pm

This doctor is intelligent and honest. I didn’t read the whole thing, but she is right about a lot.