Extra Crispr

Guest Post by The Zman

Every few months we get a blazing headline about a breakthrough in genetics that will allegedly lead to super babies. This one from a few months ago is a good example of the genre. It makes for a catchy headline. Of course, the story is never as claimed, as we are not close to creating a race of mutant super babies. Instead, science is creeping up on the ability to do some very narrow gene editing to eliminate well known genetic defects. In fact, a lab has just successfully edited a viable embryo for the first time.

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This is a huge step in science, but we are nowhere near close to creating the master race or even making small changes in real humans. The most recent research on human intelligence, for example, identifies 50 genes that correlate to IQ. That’s a lot of combination to sort, assuming that is the whole set of genes related to IQ. There’s also the possibility that other traits are indirectly related to those genes. Even something as simple as hair color can get wildly complex, so we will not be decanting babies anytime soon.

While we are nowhere near close to making super babies, this is one step down the road toward altering the foundations of human existence. The ability to inexpensively alter DNA, even in very simple ways, will lead to better food and better medicine. Imagine a treatment that alters a pathogen such that it attacks cancer cells in the human body. It sounds outlandish, but that is essentially what your immune system does with disease. Of course, the ability to “correct” genetic defects will have an enormous impact on human health.

It’s easy to fall into the science fiction fantasy stuff when thinking about these topics, but small things can have a huge impact on human behavior. Improvements in sanitation, food production and basic medicine greatly altered the human condition. Just look at the impact of life expectancy. If lifespans were still as they were a century ago, things like pension costs and health care would not be topics in politics. It is because we can live, and live vigorously, into our 70’s that these issues are now major topics.

That’s why this gene editing technology is such a big deal. Up until very recent, the consensus in science was that we were generations away from having the ability to edit human DNA. All of a sudden, the future is now and the rush is on to be the first to alter an actual human embryo and bring it to term. It also means that science will suddenly shift from the purely theoretical to the practical. The first guy to figure out how to fix defects in something as frivolous as purebred dogs will become very rich and very famous.

There’s another aspect to this that is probably more important than the potential impact on human biology. What this technology is doing is bringing to center stage a truth about humanity that our betters have been trying to suppress for generations. That is, what we are is what we inherit from our parents. What they are is what they inherited from their parents. Each of us is the result of thousands of generations of breeding. Our physical and cognitive traits are the result of that long ad hoc experiment.

At a basic level, people know this. Anyone who is familiar with human children knows that they look and act like their parents from an early age. But, people don’t think to hard about this stuff and our rulers work to keep us from thinking about how this scales up. If a white man is the result of thousands of generations of white people, that means the African is the result of his ancestors evolving in Africa. It’s not a long walk from there to accepting that race is real. That’s why this thinking is a mortal sin on our age.

This becomes increasingly difficult when it becomes more common for a doctor to use ideas and techniques from genetics to better serve his patients. The old gag about race is that race is a social construct until you need a bone marrow transplant. Not a lot of people have that talk with their doctor, but imagine a world where everyone has a genetic realism talk with their dog breeder. When you know Rover had a known defect in his breed fixed by a vet at the canine gene clinic, talking about biological reality gets a lot easier.

As people come to accept the reality of gene editing, even if it is just to make better dog breeds, it is much more difficult to maintain the mythologies of the blank slate.  Once people come to accept that things like IQ and personality traits are determined by our genes, the blank slate is finished. Even if people don’t accept genetic determinism, they will accept testing for IQ and personality traits to fill engineering positions. In other words, strides in genetics will restore a more sober understanding of the human condition.

This is the negation of the core belief of our ruling elite, but it is telling that our rulers seem to be going in the opposite direction. As science makes clear the realities of human biology, our rulers scream ever louder to the contrary. Instead of simply ignoring the new information, they are waging pogroms too root out anyone not fully committed to their biological denialism. Every week were treated to some new scandal where a heretic is brought forth and punished for acknowledging reality.

It’s common to compare our current age to the scientific revolution. Galileo is a compelling figure. That does work at some level, but what we are really experiencing is something like what happened in the Roman Empire, prior to Constantine. As the people began to embrace the new religion, the rulers tried to crack down on it. This only made the new religion more popular. The great insight of Constantine was to recognize the strategic advantage that was available to the first ruler who embraced the new religion.

That’s probably what awaits us. Science is moving along faster than the the current throne and altar cabal can follow. Some clever politician is going to embrace biological realism and ride it to victory over the prevailing orthodoxy. The first politician to say “Of course men and women are different” and not get run out of town will be the snowflake that sets off the avalanche. Regardless, breakthroughs like CRISPR are about to shake the foundation of our culture. The blank slate’s days are numbered.

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16 Comments
BSHJ
BSHJ
August 9, 2017 2:33 pm

bad joke

BSHJ
BSHJ
August 9, 2017 2:43 pm

error

Credit
Credit
August 9, 2017 2:51 pm

just posted this on the Race Realism article earlier

early adoption of gene modification techniques by the very wealthy has the possibility of creating a breakaway, superhuman society the likes of which would give Hitler a wet dream. if you think Soros is beyond his reasonable amount of time here, just wait. we risk being at the mercy of a methusalan master race through selfish legacy creation by the select, rich few. their children will have higher IQs, prettier faces, better hearing, adaptive sight, you name it. have you seen the super muscular dog the atheistic Chinese played God with…

http://www.independent.co.uk/news/science/mutant-extra-muscular-dogs-created-by-chinese-scientists-a6701156.html

peaknic
peaknic
  Credit
August 10, 2017 4:48 pm

Nancy Kress wrote a SF trilogy delving into this topic that was excellent, the first of which is called “Beggars in Spain”. The first genetic “enhancement” to be introduced in her novels was “Sleeplessness”, or the ability to live without sleep. You can immediately think of many advantages they would have what with an extra 25% – 40% of the day to get shit done…

pyrrhus
pyrrhus
August 9, 2017 3:30 pm

In fact, those 50 genes account for only a tiny amount of IQ. Probably several thousand genes relate to intelligence, and even more important, IQ is strongly related to general health and longevity. The most viable theory behind the general decrease in western IQ is the accumulation of defective mutations due to the welfare state.

peaknic
peaknic
  pyrrhus
August 10, 2017 5:10 pm

Leaded gas and more generally the widespread pollution of heavy metals in our air and water can, and has, lowered IQ for the past 2-3 generations. Even if they can modify a human’s POTENTIAL IQ, we will likely only make up for the continuing and increasing environmental assault on our IQs.

Iska Waran
Iska Waran
August 9, 2017 4:14 pm

What would people do with higher IQ’s? Read a book? All the money will be in bigger tits and dicks.

Anonymous
Anonymous
August 9, 2017 4:21 pm

TPC

Take it a step further:

Targetted apoptosis of senescent cells actually was able to reduce the visible and cellular effects of aging in mice populations. This includes the return of once lost hair, darkening of grayed hair, improvements in renal function, and appears to also peel back some of the degradation in muscle mass as well.

This wasn’t accomplished via gene-editing, but rather an actual peptide based drug that can be mass-synthesized without having to risk editing the human genome.

In layman’s terms, this appears to return your cells/body to its “homeostatic norm”….so, in theory a human would get reset to their genetically-programmed “normal” adult body, without the build-ups of oxidative damage, loss of muscle function, and destroyed collagen. Your age would be back to a 24 year old pretty much. Even the wrinkles would be gone.

All in a SHOT.

This would not make someone immortal, but would instead greatly improve a person’s quality of life through until the end of our genetically pre-programmed death…essentially that point at which the complete loss of your telomeres to telomerase degradation causes your cells to literally stop splitting.

Of course, they know how to interfere and stop that too. Its quite possible that within the next 100 years we end up with the first humans who will live to 150 or more. Crazy.

IndenturedServant
IndenturedServant
August 9, 2017 4:52 pm

Stick a fork in us……..the hooman race is extra crispy.

rhs jr
rhs jr
August 9, 2017 6:26 pm

We will soon see another more dominant fork on the Human Tree related to IQ (not the angle of the dangle or the mass of the ass).

Llpoh
Llpoh
  rhs jr
August 9, 2017 7:37 pm

Rhs – I doubt it. If anything, I would expect to see a fork where humans get much more stupid.

I believe what we are seeing is the results of Darwinism beng screwed with. Survival of the fittest no longer applies.

In recent decades, or the last century or so, people are surviving that would have been killed off. That is dramatically reducing the quality of the gene pool. The stupid are surviving, and they are breeding like rabbits.

So the gene pool is becoming dumber and dumber. I have seen projections where the world average I Q could drop to around 85 by the year 2000.

Look at Africa. The population of Africa has skyrocketed in the last 100 years, and will continue to do so. There is no more weeding out of the weak. I suspect the very low IQs of Africa relate to the weakening gene pool combined with the low nutrition, disease, etc., found there.

It will not be pretty. The weak were not meant by nature to survive. It really is that simple. The stupid, those with propensity to disease, etc., were meant to die off. That they have not, combined with the propensity of those groups to breed far more rapidly than those carrying the best genes, will lead to catastrophe.

IndenturedServant
IndenturedServant
  Llpoh
August 9, 2017 9:35 pm

+1,000,000!

We reached peak human in about 1970. It’s all downhill from here baby!

In another 100-200 years the survivors, a mixed breed of beaner, kneegrow and muslim, will be sitting around literally surrounded by an ocean of wheels wondering what the fuck they were for?

I so wish that I could pop in for a day or two every 20 years or so just to observe the decline.

FORWARD!!!———>to The Great Regression!!!

TampaRed
TampaRed
  IndenturedServant
August 9, 2017 11:36 pm

why should i-mine don’t stink–

TampaRed
TampaRed
August 9, 2017 11:45 pm

Did you guys hear about the green dog that was born in Great Britain?
It was not from gene tinkering,apparently it was from algae that mom had drunk that went thru the placenta.

Robert (QSLV)
Robert (QSLV)
August 10, 2017 1:28 pm

Most thought provoking post by Credit. Seems inevitable those in power will exclude most from any benefit and create master progeny who will control what happens to the un-modified. The population of un-enhanced humans will be managed for size, utility and control. Rebellion will be bred out and numbers will be controlled for only enough to serve the master progeny. Humans will still technically exist, but not in the way we ever remembered or dreamed of. Perhaps this has happened before and spawned legends of gods and ordinary humans?

Robert (QSLV)