Antiparasitic drug Ivermectin kills coronavirus in 48 hours

Via News Medical Life Sciences

Around the world, scientists race to develop a vaccine or treatment against the coronavirus disease (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Now, a team of researchers has found that a drug already available around the world can kill the coronavirus in a lab setting in just 48 hours.

Novel Coronavirus SARS-CoV-2 Colorized scanning electron micrograph of an apoptotic cell (green) heavily infected with SARS-COV-2 virus particles (yellow), isolated from a patient sample. Image captured at the NIAID Integrated Research Facility (IRF) in Fort Detrick, Maryland. Credit: NIAID

Novel Coronavirus SARS-CoV-2 Colorized scanning electron micrograph of an apoptotic cell (green) heavily infected with SARS-COV-2 virus particles (yellow), isolated from a patient sample. Image captured at the NIAID Integrated Research Facility (IRF) in Fort Detrick, Maryland. Credit: NIAID

The drug, Ivermectin, an antiparasitic medicine, is an inhibitor of the virus SARS-CoV-2 in-vitro and can effectively cause a reduction in virus at 48 hours in cell cultures. The FDA-approved drug can be used for repurposing to treat patients affected by COVID-19, which has spread to 184 countries and territories.

The researchers at Monash University in Melbourne, Australia, have published their study in the journal Antiviral Research, showing how this already widely-used drug may help combat the current global pandemic rippling across continents.

Reduced COVID-19 viral RNA

The team worked with the Peter Doherty Institute of Infection and Immunity. They showed that Ivermectin reduced COVID-19 viral RNA present in cell culture by as much as 93 percent after 24 hours and by 99.8 percent after 48 hours, at around a 5,000-fold reduction in coronavirus RNA, hinting that the medicine can potentially eradicate the virus.

“We found that even a single dose could essentially remove all viral RNA by 48 hours and that even at 24 hours, there was a significant reduction in it,” Dr. Kylie Wagstaff of the Monash Biomedicine Discovery Institute, said.

“Ivermectin is very widely used and seen as a safe drug. We need to figure out now whether the dosage you can use it in humans will be effective – that’s the next step,” Dr. Wagstaff added.

The researchers, however, cautioned that the tests performed in the study were in vitro, and human trials are still needed to determine the efficacy and safety of the drug against the coronavirus. Ivermectin has also shown effectiveness in vitro against a wide range of other viruses, such as the influenza virus, Zika virus, and the human immunodeficiency virus (HIV).

Repurposing Ivermectin

Ivermectin is an approved drug to treat parasitic conditions, such as rosacea, head lice, and scabies. It was developed in 1975 and has been widely used across the globe since the early 1980s.

“In times when we’re having a global pandemic, and there isn’t an approved treatment, if we had a compound that was already available around the world, then that might help people sooner. Realistically, it’s going to be a while before a vaccine is broadly available,” Dr. Wagstaff explained.

Though the mechanism of action by which Ivermectin works on the coronavirus is still unknown, the drug works on other viruses by stopping them from inhibiting down the host cells’ ability to detect and fight them.

Ivermectin, therefore, warrants further investigation for possible benefits in humans. Further trials should be performed to make sure the drug is effective. If it is effective on humans with coronavirus, it can be widely used to treat affected populations since it already went through approval by the U.S. Food and Drug Administration (FDA).

Countries grapple against COVID-19

Many countries are unprepared for the coming of the coronavirus disease, which has emerged in China in December 2019. Since then, it has spread to most countries across the globe, touching all continents except Antarctica.

The United States reports the highest infections, with more than 368,000 people affected by the virus. It has a staggering 10,923 deaths. Italy has the highest number of deaths, with its death toll reaching 16,523, while Spain has more than 136,000 confirmed cases and 13,341 deaths. Canada has more than 16,000 confirmed cases, while Germany, France, and China have more than 103,000, 98,000, and 82,000 cases, respectively.

The coronavirus has dramatically affected the United Kingdom and Australia also, with more than 52,000 and more than 5,700 cases, respectively.

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37 Comments
lamont cranston
lamont cranston
April 6, 2021 9:23 pm

Sadly, “WHO” doesn’t give a s*it.

Ed
Ed
  lamont cranston
April 6, 2021 11:13 pm

Lamont, you could have posed that as a question: “Who doesn’t give a shit?”

I could have answered ” I doesn’t”.

Seriously, though, ivermectin, like quinine is effective as a treatment for coronaviruses in general. Both are antiparasitic drugs. WHO is made up of parasites, willing to lie to further political agendas. maybe they are avoiding any recognition of ivermectin in the same way vampires avoid crosses.

TheAssegai
TheAssegai
April 6, 2021 9:46 pm

Click on “Via News Medical Life Sciences” at the top of the article and it dates the article in 2020.

“coronavirus disease (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)”
I am not aware of anyone who claims that SARS-CoV-2 has been isolated; no one claimed to have isolated the virus in 2020 or to today in 2021.

The image that is shown was taken at…….wait for it…….wait for it…..NIAID Integrated Research Facility (IRF) in Fort Detrick, Maryland. Credit: NIAID. Fort Detrick, something about the name rings a bell, that’s right – MK-ULTRA, for starters. And credit goes to NIAID, again, there is something about that name, that’s right, that’s the place where one little guy by the name of Fauci was appointed director in 1984. Appointed director in 1984, that year rings a bell, no not possible.

Anonymous
Anonymous
  TheAssegai
April 6, 2021 10:52 pm

So sad that a full year later from this article’s print and Ivermectin is still not getting traction when it has been shown over and over again to be effective. I really prefer to believe it is due to nefarious reasons and not that the world is just full of morons. Though I suppose it could be a combo huh….

TheAssegai
TheAssegai
  Anonymous
April 6, 2021 11:12 pm

There is Hanlon’s razor which states “never attribute to malice that which is adequately explained by stupidity”. But for me this is just too well planned and too many coincidences to just be happening and there is no debate, everything was settled at the very beginning, a vaccine was the only way out. While I think this is just the ‘flu’, after all deaths this year are consistent to previous years, where is the fear if you can buy a $5 bottle of Ivermectin, or lay in the sun to generate vitamin D or eat an orange for vitamin C. No fear no control.

Ed
Ed
  TheAssegai
April 6, 2021 11:20 pm

“I am not aware of anyone who claims that SARS-CoV-2 has been isolated; no one claimed to have isolated the virus in 2020 or to today in 2021.”

I’m aware of a few retards on Unz review who pass off this link as a claim that the virus has been isolated and sequenced:
https://www.ncbi.nlm.nih.gov/datasets/coronavirus/genomes/

Jon Rappaport dealt with that one, and when I linked to one of his articles in response one of the trolls replied that Jon is full of shit as evidenced by his surname which identifies him as an Eevull Joo.

I shit you not.

TheAssegai
TheAssegai
  Ed
April 6, 2021 11:37 pm

Rappaport has not only been on this issue from the start, but he was on the fact that HIV (another so called virus) was not the cause of AIDS. There are hundreds of thousands of dollars in rewards for anyone that can prove that SARS-CoV-2 has been properly isolated, but as far as I know the reward has not been given out. I might add also that none other than Fauci was the main instigator of the HIV AIDS lie. I think the number world wide was in the millions that died as he pushed AZT as the cure, a failed cancer drug and a failed AIDS drug, not unlike now he is pushing Moderna, which is also from a cancer lab.

Anonymous
Anonymous
  TheAssegai
April 7, 2021 2:32 pm

https://en.wikipedia.org/wiki/GISAID#

The GISAID Initiative was initially funded by Peter Bogner—a strategic advisor and international broadcasting executive—who serves as its founder and principal facilitator. Bogner has been directing the build-up of this platform by bringing together the world’s leading scientists and stakeholders who are actively committed to accelerating understanding of this potential human pandemic by rapidly sharing scientific data and results. In January 2006, Bogner met with US Secretary of Homeland Security Michael Chertoff at the World Economic Forum in Davos, Switzerland, and was told about the US government’s preparedness concept on dealing with the potential of a flu pandemic.[24] Concerns about a pandemic scenario heightened.[25]

TheAssegai
TheAssegai
  Anonymous
April 7, 2021 3:32 pm

I am not entirely clear because you simply linked to a Wiki article, but my assumption is that you are using a Wiki posting to refute my claim that SARS-CoV-2 has never been isolated.
1. By sole sourcing a Wiki article you do know that you have basically confirmed that you have no clue nor any evidence. Look into Wiki and you will come to that understanding as well.
2. SARS-CoV-2 has never been purified and isolated! The closest they have come is to synthetically produce something that they call the virus. The synthetic thing was done in a petri dish which included all sorts of foreign substances.
3. GISAID is a PPP, that alone should be of concern. I do not know of a source directly relating to PPPs, but I suggest that you read John Perkin’s ‘Confessions Of An Economic Hitman’ as well as F. William Engdahl’s ‘Manifest Destiny’. Those two books on international funding and NGOs will enlighten you on PPPs.
4. The article references Michael Chertoff, have you no clue who Chertoff is or what he was involved with? Chertoff is as dirty as they come.
5. For god sakes, Bogner and Chertoff met at the WEF in Davos, have you no idea how foolish that makes your entire Wiki article?

Anonymous
Anonymous
  TheAssegai
April 9, 2021 10:36 pm

Actually, points 2-5 were exactly the point of my posting it. Sorry I wasn’t clear.

That I got it from wikipedia only indicates that it is (for now, at least) publicly accessible knowledge.

If you click the link to the third cited article at the bottom of the post:

https://www.sciencedirect.com/science/article/pii/S0166354220302011

You’ll see that they reference the “isolated virus” as (Australia/VIC01/2020 isolate).

Search that, minus the parentheses, and you’ll get a few articles, organizations and links which all eventually circle back to GISAID, this guy Bogner, and Chertoff, … and the beginning was in 2006 at WEF.

The point was that I smell a rat in the “isolation” and “gene sequencing” (via PCR, btw) of this virus, and that this 2006 Davos meeting may have been a crucial spark for hatching a Plan-demic.

brian
brian
April 6, 2021 9:57 pm

Brilliant… These dirtballs will push in a matter of weeks to a month completely experimental gene therapy elixirs that have ZERO known side effects long term. They know what the short term is producing, like death, clots, blindness, anaphylactic shock, etc.

Then they drag their heels on a drug KNOWN to be effective against other viruses. One thats been used for decades safely but now they have to run ‘studies; to see if it will work in humans and if its effective. I call BULLSHIT. These scum have no trouble killing people for profits. They need to be hung.

Doctor de Vaca
Doctor de Vaca
April 6, 2021 10:10 pm

Gotta love Cow Meds

I'm the Man on the Silver Mountain
I'm the Man on the Silver Mountain
  Doctor de Vaca
April 7, 2021 1:07 pm

Exactly.
Ivermectin is just another brand name of effective parasite medication used to kill or remove heartworm. It’s given to dogs and cats by vets but the people running a UN organization are too fucking stupid or corrupt to decide it’s fine for people.
This is why conspiracy theories gain valid traction.

KaD
KaD
April 6, 2021 11:16 pm

European Medicines Agency Official: “Clear Link” Between AstraZeneca Vaccine and Blood Clots in the Brain

Joe Blow
Joe Blow
April 6, 2021 11:29 pm

Note this article is from April 6, 2020. Seems it was memory holed for obvious reasons.

Anonymous
Anonymous
  Joe Blow
April 7, 2021 1:42 am

* rea$on$

Doc Adams
Doc Adams
April 7, 2021 3:52 am

Durvet is readily available at farm and ranch stores. Horses sometimes are smarter than people.

https://www.tractorsupply.com/tsc/product/durvet-ivermectin-paste-187-608-g

Chemist46
Chemist46
April 7, 2021 5:21 am

Dr. Ryan Cole Blows The Whole COVID-19 Propaganda Away

Dr. Ryan Cole Blows the Whole Covid-19 Propaganda Away

very old white guy
very old white guy
April 7, 2021 6:06 am

Doctors around the globe are using ivermectin and they say it is working, more tests are not needed, just more use.

BUCKED/BUY MORE AMMO/BOURBON TOO
BUCKED/BUY MORE AMMO/BOURBON TOO
April 7, 2021 6:46 am

As I’ve stated on this forum I personally know someone that was on the verge of being hospitalized with Covid and was given Ivermectin and was fine in two days .

It is my sincere hope that those who have perpetuated this Plandemic Fraud will be jailed and that history will paint them as the evil that they are.

ReluctantWarrior
ReluctantWarrior
April 7, 2021 7:48 am

I know this to be true. I had two friends who used it accordingly to treat COVID and it worked like a charm. Don’t listen to the fools at the FDA,CDC or WHO. Idiots!

Guest
Guest
April 7, 2021 9:16 am
Shotgun Trooper
Shotgun Trooper
April 7, 2021 10:01 am

That’s why Africa has had no huge outbreaks of COVID, they’ve used the anti-parasitics extensively for years. Africa was projected to be devastated by COVID….. Crickets.

KYLE BOATWRIGHT
KYLE BOATWRIGHT
April 7, 2021 10:08 am

A family friend was diagnosed with COVID-19 the first of March. Older gentleman (70’s). My wife talked him into asking his attending MD for an Ivermectin prescription. This MD agreed and wrote the script (sent electronically to pharmacy). When picking up the prescription, the pharmacy refused to fill the prescription citing that there was no approved COVID-19 treatment and would not fill the Ivermectin prescription. We tried several pharmacies with the same result. Eventually, my wife called the hospital, told them their MD wrote a script and no pharmacy would fill it. They eventually agreed to fill it thru the hospital contract pharmacy in a town 40 miles away. We picked up the script, the patient started the Ivermectin and felt better in a few days…

This thing goes thru pharmacies, insurance, big pharma, .gov, and MDs… No time ever has a patient been diagnosed with a disease and told, well go home and if you get really sick, we’ll put you on a ventilator…

brian
brian
  KYLE BOATWRIGHT
April 7, 2021 10:26 am

The fact that a pharmacist can refuse to fill a script from a doctor is problematic in itself. THAT right there should be prosecutable. Since when is a pharmacist able to diagnose and treat patients according to their ‘training’??

Jdog
Jdog
  brian
April 7, 2021 12:12 pm

Correct. Pharmacists are not doctors. They fill orders for the doctors. For a pharmacist to refuse to fill a legitimate prescription for a doctor is a criminal act for which they should be prosecuted… or worse.

Mygirl....maybe
Mygirl....maybe
  KYLE BOATWRIGHT
April 7, 2021 11:40 am

The Covid was the excuse to vaccinate. Can’t have any cheap, effective treatments when a vaccine(s) can be used to not only control the population but also reduce the population. I don’t know about J&J but the mRNA vaccines are truly scary. One wonders if the vaccinated are now super carriers, shedding mutated virus or if the vaccine will activate at a later date and start killing people.
Go do yourself a favor, go to the Tractor Supply or some other place that sells animal meds and get a tube of horse paste. The tube has a dial that is used to determine dosage according to weight. Ivermectin is weight specific as regards dosage. It supposedly tastes like chalk but so what. One tube is less than five dollars.

grace country pastor
grace country pastor
  Mygirl....maybe
April 7, 2021 1:23 pm

I bought apple flavored, still… 🤮

But it worked in under 24 hours!

mark
mark
  grace country pastor
April 7, 2021 5:19 pm

Ted,

That is an interesting story…details?

mark
mark
  Mygirl....maybe
April 7, 2021 5:17 pm

Mygirl,

I bought some Ivermectin through this website months ago, Yo put it up:

https://deep-survival4.mybigcommerce.com/

I went back to get come more…for family, but they have closed down. Hmmm…it was called Deep Survival and had all types prepper drugs, medical supplies.

I have had a large stash of HCQ for seven or eight months.

I was in a local independant farm/feed store today like Tractor Supply (called Southern Supply) and they have three brands of Ivermectin horse paste all around $8.00 a tube.

What the heck, I’m going to get one of each and add it to my human Ivermectin, HCQ stash plus my D3 (with K2), Zinc, L-Lysine, Liposomal Vit. C, Quercetin, Brazil Nuts (two a day for Selenium) last but never least a half dozen bottles and topical tubes of Collodial Silver.

I have it all on a table in a storage room with dosages and what each one does in a note book for my family in case something happens to me.

GNL
GNL
  mark
April 7, 2021 9:09 pm

Mark,

I think you can get Ivermectin at http://www.myfreedoctor.com now.

TampaRed
TampaRed
  mark
April 7, 2021 10:31 pm
Jdog
Jdog
April 7, 2021 12:06 pm

This is simply more proof that the governments and pharmaceutical companies are not really interested in curing the virus. Their agenda is to introduce RNA vaccines as the standard treatment. The reason they are obsessed with this is because the vaccines can be designed to target or exclude certain groups.
The level of evil of the people in power is inconceivable to the average person…

I'm the Man on the Silver Mountain
I'm the Man on the Silver Mountain
  Jdog
April 7, 2021 1:27 pm

It’s a known fact that psychopaths lack empathy and we’re governed by psychopaths who also run our corporations and institutions.
At some point the immorality, greed, corruption, and psychopathology will result in a very large Singularity event where the rest of us will be required to deal with the consequences.

Soon.

Ken31
Ken31
April 7, 2021 3:51 pm

Fig. 1. Ivermectin is a potent inhibitor of the SARS-CoV-2 clinical isolate Australia/VIC01/2020. Vero/hSLAM cells were in infected with SARS-CoV-2 clinical isolate Australia/VIC01/2020 (MOI = 0.1) for 2 h prior to addition of vehicle (DMSO) or Ivermectin at the indicated concentrations. Samples were taken at 0–3 days post infection for quantitation of viral load using real-time PCR of cell associated virus (A) or supernatant (B). IC50 values were determined in subsequent experiments at 48 h post infection using the indicated concentrations of Ivermectin (treated at 2 h post infection as per A/B). Triplicate real-time PCR analysis was performed on cell associated virus (C/E) or supernatant (D/F) using probes against either the SARS-CoV-2 E (C/D) or RdRp (E/F) genes. Results represent mean ± SD (n = 3). 3 parameter dose response curves were fitted using GraphPad prism to determine IC50 values (indicated). G. Schematic of ivermectin’s proposed antiviral action on coronavirus. IMPα/β1 binds to the coronavirus cargo protein in the cytoplasm (top) and translocates it through the nuclear pore complex (NPC) into the nucleus where the complex falls apart and the viral cargo can reduce the host cell’s antiviral response, leading to enhanced infection. Ivermectin binds to and destabilises the Impα/β1 heterodimer thereby preventing Impα/β1 from binding to the viral protein (bottom) and preventing it from entering the nucleus. This likely results in reduced inhibition of the antiviral responses, leading to a normal, more efficient antiviral response. L. Caly, et al. Antiviral Research 178 (2020) 1047873

I don’t know why the image won’t post

Ken31
Ken31
  Ken31
April 7, 2021 3:59 pm

i give up

Anonymous
Anonymous
  Ken31
April 7, 2021 6:27 pm

comment image